Depression is a growth industry now. Prozac and its cousins Paxil
and Zoloft are now three of the top six largest selling prescription
drugs. Considering that these pills are really only slightly more
effective than their predecessors - that is, only a little more effective
than placebo - their acceptance by both healthcare professionals and
the public has been amazing. New reports suggest it's not just amazing,
it's corruption.
Ever since Arrowsmith there's been a question about whether for-profit
pharmaceutical manufacturers can sponsor truly objective scientific
research. Dr. Martin Keller of Brown University has been a respected
researcher into depression for decades. He has many, many publications
and grants to his credit, some of which have been the foundation for
much of our current knowledge about the course, causes, and treatment
of this disease. Now the Boston Globe reports that Dr. Keller
has been getting rich on payments from some of the drug companies
whose products he's been researching. In 1998 alone, Dr. Keller pulled
in $556,000 in consulting fees from these companies. That's not grants
to fund research, or reimbursement for expenses, or even lavish little
conferences in the Caribbean - that's direct cash money into his pocket.
In addition, the Globe reports that Dr. Keller did not disclose
the extent of his relationships to these companies to the medical
journals that published his findings or to the professional associations
that sponsored the conferences where he presented his findings.
There's no evidence yet that Dr. Keller cooked his data or slanted
his conclusions because of these payments. But we know that kind of
thing happens often enough in science just because researchers have
an emotional investment in reaching a certain conclusion. Dr. Keller's
whole body of work, much of it probably quite good, is now open to
question because of these revelations.
Pharmaceutical manufacturers are constantly telling us that the high
prices we pay for prescription medicines go to help them fund research
into new drugs. I don't know about anyone else, but I'd be willing
to pay a lower price and a higher tax, and let the government fund
research. Profits and healthcare are a dangerous combination.